Solvent‐Cast Polymeric Films from Pectin and Eudragit® NE 30D for Transdermal Drug Delivery Systems

In this study, solvent-cast polymeric films containing ionic liquid lidocaine/aspirin for transdermal patches were developed. Solvent-cast prepared from two polymers, pectin and Eudragit® NE 30D, by drying the solution in a hot air oven at 70 ± 3 °C 10 h. Glycerin was used as plasticizer. Lidocaine aspirin form loaded into patches. The physicomechanical properties of characterized texture analysis, differential scanning calorimetry, thermogravimetric X-ray diffraction. A electron microscope to photograph surfaces films. 30D significantly decreased toughness rigidity amorphous state, their thermal not changed blank rougher than revealed distribution drug. trends entrapment efficiency vitro release lidocaine drugs. kinetic observed fitted Higuchi’s model rather zero first order models, indicating that diffusion mechanism governed drug patch. Thus, are suitable with lidocaine/aspirin.